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COVID-19 Vaccines and Neuropsychiatric Risks: Study Insights

July 7, 2025 • by DailyClout

The potential link between COVID-19 vaccination and neuropsychiatric conditions has sparked significant interest in recent medical research. A peer-reviewed study, “View of Association Between COVID-19 Vaccination and Neuropsychiatric Conditions,” published in the International Journal of Innovative Research in Medical Science investigates this connection, offering insights into post-mRNA COVID vaccination adverse effects related to brain function and behavior.

What the Study Examined

The study, conducted by a team of researchers including Thorp, Rogers, Cosgrove, Hatfill, Breggin, Pinsky, and McCullough, aimed to explore whether COVID-19 vaccination and neuropsychiatric conditions are associated. Using data from the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration’s (FDA) Vaccine Adverse Event Reporting System (VAERS), as well as the the CDC and FDA’s statistical methodology for detecting safety signals, the researchers analyzed reports of adverse events (AEs) related to neuropsychiatric issues following COVID-19 vaccination. The study compared these events to those reported after influenza vaccinations and all other vaccines over a specific timeframe.

The data spanned from January 1, 1990, to December 27, 2024, covering 420 months for all vaccines and 48 months for COVID-19 vaccines, which have only been available since late 2020. The researchers used a statistical measure called the Proportional Reporting Ratio (PRR), which is what is used by the CDC and FDA, to identify potential safety concerns. According to CDC/FDA guidelines, a PRR of 2 or higher indicates a possible safety signal, meaning the adverse event occurs at a rate that warrants further investigation.

In this study, the PRRs listed for neuropsychiatric conditions ranged from two to 440. According to CDC and FDA guidelines, a PRR greater than or equal to two, when accompanied by statistical significance, like the ones in this study were, suggests a potential safety signal. This means the adverse event may occur more frequently than expected and warrants further investigation to determine if the drug/vaccine is causing the event.

Key Findings

The study identified 86 serious neuropsychiatric safety signals associated with COVID-19 vaccines when compared to influenza vaccines. These signals suggest a higher likelihood of certain neuropsychiatric conditions following COVID-19 vaccination. Below are the most significant findings:

  • Psychosis: The study found that psychosis was 440 times more likely to be reported after COVID-19 vaccination compared to influenza vaccination. This is a striking figure, indicating a significant safety signal.
  • Other Neuropsychiatric Conditions: The study identified safety signals for conditions such as anxiety, depression, and cognitive impairment, though specific PRR values for these conditions were not detailed in the summary.
  • Comparison to Other Vaccines: When compared to all other vaccines, COVID-19 vaccines also showed elevated PRRs for neuropsychiatric adverse events.
  • Statistical Significance: The safety signals were calculated with 95% confidence intervals and p-values, ensuring the findings met rigorous statistical standards. A PRR ≥ 2, as defined by the CDC/FDA, was consistently observed for the identified neuropsychiatric conditions.

These findings suggest that COVID-19 vaccination and neuropsychiatric conditions have a stronger association than previously disclosed.

Why This Matters

The study contributes to the ongoing conversation about vaccine safety, particularly for mRNA COVID-19 vaccines, which were developed and rolled out very rapidly. Understanding the potential risks is crucial for informed consent. The identification of 86 neuropsychiatric safety signals underscores the importance of actively monitoring vaccine side effects, especially for conditions that can significantly impact quality of life.

For individuals considering vaccination or concerned about side effects, this study suggests discussing known mRNA COVID-19 vaccination risks with healthcare providers. It also highlights the value of systems like VAERS in detecting potential issues early, allowing researchers to investigate further.

Limitations of the Study

The study has some limitations that readers should keep in mind:

  • VAERS Data: As a passive reporting system, VAERS cannot confirm causation, and reports may include incomplete or inaccurate information.
  • Timeframe Differences: The 48-month availability of COVID-19 vaccines compared to 420 months for other vaccines may skew comparisons.
  • Complexity of Neuropsychiatric Conditions: These conditions are influenced by many factors, making it challenging to isolate vaccines as the sole cause.

Even with such limitations, the study’s rigorous methodology and use of CDC/FDA safety thresholds make it a valuable contribution to the field.

What’s Next?

The researchers call for further studies to explore the mechanisms behind these potential associations. For example, future research could investigate whether specific vaccine components or individual health factors contribute to these adverse events. Regulatory agencies like the CDC and FDA may also use these findings to guide vaccine safety monitoring.

For the public, this study is a reminder of the importance of staying informed and engaging in open discussions with healthcare professionals. Knowing and understanding the full range of mRNA COVID-19 vaccine adverse events is essential for making informed healthcare decisions.

Closing Thoughts

The study on COVID-19 vaccination and neuropsychiatric conditions provides important insights into potential vaccine-related adverse events. By identifying 86 safety signals, including a significant association with psychosis, it highlights areas for further research and gives patients more information for deciding whether or not to risk a gene therapy “vaccination.” These findings encourage ongoing vigilance and dialogue about vaccine safety.

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#FDA CDC COVID-19 vaccination drug safety medical research neuropsychiatric conditions operation warp speed peer review peer reviewed study psychosis public health surveillance vaccine safety VAERS
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