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Pfizer Documents Analysis Reports - Pfizer

Internal Report 27: “The Underlying Pathology of Spike Protein Biodistribution in People That Died Post COVID-19 Vaccination”

August 3, 2026 • by Dr. Arne Burkhardt—Compiled and Edited by Robert W. Chandler, MD, MBA* and Michael Palmer, MD

The Scientific and Medical Advisory Committee hosted a meeting with special guest speaker Professor Arne Burkhardt. *A transcript was produced then edited with a diligent effort to leave the meaning unchanged. My additions are in italics.

Professor Burkhardt was a German pathologist and researcher. He presented the findings of the ongoing work of an international team of pathologists. They have reviewed pathology specimens from people with new onset of symptoms or who have died following COVID-19 genetic vaccinations. He explained how to differentiate damage following natural infection with that following vaccination. Additionally, he presented tissue samples to illustrate the distribution of the spike protein following COVID-19 genetic vaccination and its associated damage, amyloid production, and clot formations.

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Original Lecture—“Arne Burkhardt Presentation to the CCCA”

(https://rumble.com/v2jbj16-arne-burkhardt-presentation-to-the-ccca.html)

Professor Arne Burkhardt

Transcript I will tell you that actually very soon after the vaccine campaign started in Germany, there were relatives of deceased persons who went to me and said, well, we want to, we want that a pathologist takes a second opinion. We don’t believe that our relative died of natural causes. And I thought this was an easy task. I said, well, of course, I will look at the slides or the specimens that were taken during autopsy, and I will give a second opinion. But very soon with the first three or four cases, I realized that this was really a task that I could not handle just by myself alone. And fortunately, I found a pathologist who worked with me, Professor Walter Lang.

Professor Walter Lang

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He joined me in these endeavors and very soon we got many more scientists and some pathologists, especially from outside of Germany, who joined us in these endeavors. And if I can show my first slide now. So, at this moment we are actually an international team. It’s about 10 pathologists, coroners, biologists, chemists, and physicists, not only from Germany, but actually many European countries, especially Austria, Switzerland, Italy, and Sweden. We have completed the review of 75 autopsy studies, and we are right now having 41 biopsies from living persons. There are 40 men, 35 women of the deceased. The age range was from 21 to 94 ages.

Deaths occurred one day or to six months after the most recent injection. And the vaccines are those that are commonly used in Germany. Pfizer-BioNTech vaccine was the most common, but sometimes it was in connection with other vaccinations. The autopsies were done by pathologists, by coroners, and one by both. So, you see it’s about equal distribution. The primary diagnosis was natural death in 63 cases. And, in five cases, it was termed uncertain. So that makes 91% not related to the vaccination. Only in seven cases it was stated that there might be a correlation with the vaccination and the disease. We did the second opinion, and these are our results. I will show you histological findings.

We saw a correlation of vaccination and the death occurrence in 21 cases, and in 37 cases it was probable. So, that is 77%. In another 14 (19%), we said it was uncertain or possible, ruled out in only one case, and two cases were not evaluable.

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Sudden Adult Death Syndrome

This is the evaluation of 19 cases where they died. This is one important thing that most of the diseased we evaluated died suddenly, mostly at home, in the street, in the car, at work. So, we can rule out any post-mortem changes of the organs. There’s no artificial respiration or anything like that. So, of these 19 cases, 15 (79%) fulfill the criteria for what is now called the Sudden Adult Death Syndrome. And this is very important because I will come to the possible causes of this syndrome later.

COVID-19 vs. Modified mRNA (modRNA) Now, at the beginning it was clear that there is a difference between the natural COVID-19 infection and the messenger modified RNA vaccination, but in both sets a spike protein that is probably the most important action that does harm to the tissues.

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Now the COVID-19 infection, of course, has, besides a spike protein, other antigenic and possibly toxic agents like the nucleocapsid and others, and in the vaccination beside the spike protein, which of course is the leading mechanism. We have the lipid nanoparticles, we have cholesterol, and in some cases, contamination. From the beginning, we realized that there’s a different entry or primary target of these toxic and antigenic agents and the infection. It’s the epithelium, starting from the nose, from the eye, pharynx, airways, lung. And these are immunocompetent linings of the body. And also, there’s some protection by mucus and keratin. Now, in the vaccination we do not use this natural entrance, but it is directly shot into the interstitial tissue, the basal tissue and the endothelium. And these are non-immunocompetent.

Methodology We used normal histology (hematoxylin and eosin stain), special stains, immunohistochemistry, and in some cases advanced physical chemical methods. From the beginning on, it was clear to us that this was a novel examination because we had to demonstrate a toxin that was produced by the body itself, the spike protein. And this had to be differentiated from lesions induced by true viral infections. And, as the body produces these toxins, we have to look for the toxin in the organs and tissues of the organ itself, which produce it, and not in body fluids or in the gastric contents.

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Immunohistochemistry: Spike (COVID-19 + modRNA) vs. Nucleocapsid (COVID-19) So, we applied the method of immunochemistry to show the spike protein on the one hand and nucleocapsid on the other hand. Maybe most of you probably know the mechanism of immunochemistry is to have some stained material that binds to the protein that you are looking for. You see here some positively stained cells for spike protein from a nasal swab.

And this method was used to demonstrate the spike protein and, on the other hand, in some cases we excluded or found nucleocapsid.

General Lesions Affecting More Than One Organ (See Supplemental Resources SR 1-SR 5.)

First of all, we have general lesions affecting more than one organ. And, this is the expression of the spike protein S1. (See SR 1 and SR 2.)

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Then, we have especially the detrimental causes on the vessels because, no matter how you inject the vaccine, it will always go into the blood and lymph vessels. We found what is called an endotheliitis. It’s an inflammation and destruction of endothelium. And also, the larger vessels and the aorta are an aim of this toxic action. It’s a disturbance of the texture and the destruction of elastic fibers in the larger vessels. When we started, it was put forward by the pharmaceutical companies that it stays in the deltoid muscles where it was injected and that the muscle cells and maybe some other interstitial cells would produce the spike protein and cause the immunological reaction that they planned to.

Expression of Spike Protein

Here we examined the deltoid muscle in one case, and you can see this granular markation (black arrows) of the muscle cells. Spike protein was produced at the spot of injection.

Then we also found it in capillaries (black arrows). Here you see in fat tissue, you see the vacuoles and you see this capillary. Here it is out of the planar section, and here you can see it is cut vertically and you can see the endothelium strongly expresses a spike protein.

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Endotheliitis The spike protein, as you know, as we know now, it’s a toxic agent and it harms the endothelium as we will see later.

It is also found in other vessels in the surrounding, and you can see here an arteriole with a clear markation of the endothelium and some also in cells of the vessel walls. And this is a nucleocapsid stain of the same vessel. As you may see, it’s a completely negative reaction.

Here you can see at the site where the injection was performed. We can see still, for a very long time, inflammatory reaction in some cases. (See SR 3 and SR 4.)

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This is a biopsy from this person that you’ve just seen. You can see that in the lymph node a strong demonstration of the spike protein. After that, the spike protein is distributed or can be demonstrated in many organs, almost all organs, more or less.

Spike in the spleen.

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Spike protein in brain tissue.

Spike protein in aorta.

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Spike in testis.

Spike in prostate.

There’s some publication now about the effects on male fertility.

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Post-modRNA lymphocytic infiltration in ovary.

Post-modRNA lymphocytic infiltration in endometrium.

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Post-modRNA lymphocytic infiltration in placenta.

Post-modRNA lymphocytic infiltration in placenta and spike.

So, this is the first round about the general regions that we found.

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Displaced Unidentified Vacuolar and Crystal Particles And we come now to the displaced vacuole and crystal particles at the proteinaceous deposits.

First of all, we found in some cases in the lung and also in other organs, these foreign body giant cells with these needle-like in inclusions (black arrow). Now we know these inclusions to be so-called “cholesterol needles.”

In addition, we found some other material there, and you can see that in the periphery you can see a birefringence of these materials (white arrow).

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And then we found, in many organs, these rod-like particles (red arrows) which are in vacuoles (previous image). Now, these probably don’t form vacuoles, but they contained lipids, which like in the fat tissue are extracted during preparation. First of all, we overlooked these particles, because we thought it was so called formalin pigment, which is very well known to pathologists to be an artifact.

But we came to the conclusion that this is definitely not an artifact but that they must be some kind of material which is formed in the process of this vaccination. You can see some of these are also birefringent (white arrow). We thought a lot about where this comes from. It could come from the injection itself, but the mass that we saw was not compatible. It’s just I think it would not be possible that so much material is injected. Also, the production of some substances could be the cause for these; but from, Raman Spectrometry, we had the notion that it could be cholesterol. And then we figured out that where cholesterol is located in the human body.

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And, as you may know, now, this is not a vaccination victim. This is a normal person who died of natural causes, but he had this large arteriosclerotic plaque with perforation, and this contains, of course, masses of cholesterol.

And just to show you the scheme of the aorta—you can see that the atheroma contains these needle-like cholesterols. And, if the epithelium is destroyed, it might come into the blood circulation. (Cholesterol embolus after erosion of the inner lining of the artery overlying the plaque.) And secondary destruction could be due to the endothelial lesions of the vasa vasorum.

And here you can see a 55-year-old man, the aorta, and you can see that he has some atheromatous plaques; and you can see that one of them has broken open (red arrow), and the contents of these atheromatous plugs went into the blood.

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And we can show this because, in the spleen of this person, we found these foreign body giant cells with cholesterol needles (black arrows), and this seems to be very reasonable that this is one of the sources of cholesterol in the in the organs of the deceased after vaccination.

Amyloid Formation (See SR 6.) We come to the so-called “amyloid formation.” It was Swedish authors which found that the peptide sequences of the spike protein might be similar to amyloid and that amyloid-like substances may be formed.

(The yellow arrow points to amyloid in the vessel wall.)

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Very early we recognized that here was a strange extracellular deposit of strongly eosinophilic proteinaceous material in the vessel walls of many of the deceased that we looked at (previous image).

And, in some cases, even the vessel wall, here in the spleen, was occluded, and with the Congo Red stain these vessel walls are strongly positive. So, we confirmed that this is an amyloid deposition (yellow arrow).

And this is a skin biopsy from a living person. She had problems of perfusion, blood perfusion. You can see also that a small subcutaneous vessel has some amyloid-like material (black arrow).

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Clot Formation Now we come to the so-called “clot formation.” You may all be aware of these reports from undertakers that they found something that they never saw before; that there were some clots that were of elastic property.

And, the only thing they said is that it was not a thrombus, but some (inaudible). That’s why they are called it a clot. And, until now, we do not know exactly what it is, but it’s definitely not a thrombotic event. Because no person would survive these clot formations.

But we have a very interesting observation. We have this 40-year-old woman of around 40, which was an active marathon runner. And after one vaccination with Comirnaty, she was hardly able to walk because she had this very severe disturbance of a perfusion of her lower legs.

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And, in the radiograph, there was a dissection of the arteries of the lower leg.

And, in the skin biopsy that was taken from her, we found these lesions of the small vessels, and you can see that the endothelium is swollen. It is detached from the basal membrane. And in these vessels, we could clearly demonstrate the spike protein.

And this is from a living person. It’s definitely not an autolytic artifact. And, in this person, and this is the interesting part of it, blood samples were taken; and, after centrifugation and cooling, these clots were formed. There they are definitely separated from this part of the centrifugation.

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And we were asked, “Well, will you examine these clots formed by this lady after the cooling?” and we did this.

Here you can see this is the clot that we took, and you can see the histology, it’s a proteinaceous-fibrous material which seems to be gross outgrowths on the periphery.

And there are some lymphocytes in there. It’s not mature fibrin but fibrinogen, and we did some examination on it.

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And you can see the top plasma phase and the clot derived from the plasma phase (previous image).

And there were 137 clot enriched proteins that were not found in the serum. These are all elements from the:

  1. Vessel walls,
  2. Extracellular matrix collagen,
  3. Collagen-containing extracellular matrix,
  4. Collagen binding,
  5. Laminin binding,
  6. Elastic fiber, and
  7. Cell adhesion binding molecule.

So, the conclusions that were drawn from this finding is that the endothelial damage persisted in this unlucky lady.

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In the previous image, you can see a scheme. This is the endothelium, and, if the endothelium is destroyed by the spike protein, the spike protein goes to the deeper layer. And these constituents reach into the blood. So, I think this is demonstration that the endothelial damage is very important and may persist for a very long time. Specific Organ and Tissue Lesions (See SR 7.) We come to the specific organ and tissue lesions, and we start with the main pathological findings in the blood vessels, the small vessels.

I already showed you the

  1. Endotheliitis most prominent in the heart, lungs and brain,
  2. Aggregation of erythrocytes,
  3. Hemorrhage and bleeding,
  4. Hemosiderosis into the vessel wall,
  5. Complex formation of amyloid-spike protein-fibrin in the vessel walls,
  6. Amyloid-like deposits,
  7. Thrombocyte aggregates, and, finally,
  8. Obliteration of small vessels.

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